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SRSF2 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects SRSF2 in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN357967
发货至: 中国
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Quick Overview for SRSF2 抗体 (N-Term) (ABIN357967)

抗原

See all SRSF2 抗体
SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SRSF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects SFRS2 (N-term).

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SFRS2.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    SRSF2 (serine/arginine-Rich Splicing Factor 2 (SRSF2))

    别名

    SFRS2 / SC-35

    背景

    SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3' and can bind to beta-globin mRNA and commit it to the splicing pathway.Synonyms: Nuclear Speckle Marker, PR264, Splicing component 35 kDa, Splicing factor SC35, Splicing factor arginine/serine-rich 2

    分子量

    25476 Da (splicing protein is 35 KD).

    基因ID

    6427, 9606

    UniProt

    Q01130
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