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Doublecortin 抗体

This anti-Doublecortin antibody is a 兔 多克隆 antibody detecting Doublecortin in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN357927
发货至: 中国

Quick Overview for Doublecortin 抗体 (ABIN357927)

抗原

See all Doublecortin (DCX) 抗体
Doublecortin (DCX)

适用

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宿主

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克隆类型

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多克隆

标记

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This Doublecortin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects DCX.

    纯化方法

    Protein A Chromatography followed by peptide affinity purification.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S128 of human DCX.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    Doublecortin (DCX)

    别名

    Doublecortin

    背景

    In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.Synonyms: DBCN, DCX, Doublin, LISX, Lissencephalin-X, Neuronal migration protein doublecortin

    分子量

    44925 Da

    基因ID

    1641, 9606

    UniProt

    O43602
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