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ITGA6 抗体 (Isoform 2)

ITGA6 适用: 人 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357904
发货至: 中国
  • 抗原 See all ITGA6 抗体
    ITGA6 (Integrin, alpha 6 (ITGA6))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform 2
    适用
    • 118
    • 53
    • 25
    • 21
    • 16
    • 13
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 70
    • 38
    • 17
    • 2
    克隆类型
    • 65
    • 60
    多克隆
    标记
    • 69
    • 12
    • 11
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGA6 antibody is un-conjugated
    应用范围
    • 79
    • 49
    • 47
    • 44
    • 23
    • 20
    • 13
    • 13
    • 12
    • 12
    • 10
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects ITGA6 (Isoform 2).
    交叉反应 (详细)
    Species reactivity (expected):Chicken.
    Species reactivity (tested):Human.
    纯化方法
    Protein A Chromatography followed by peptide affinity purification.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S1064 of human ITGA6 isoform 2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ITGA6 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    ITGA6 (Integrin, alpha 6 (ITGA6))
    别名
    CD49f / ITGA6 (ITGA6 产品)
    别名
    CD49f antibody, ITGA6B antibody, VLA-6 antibody, 5033401O05Rik antibody, AI115430 antibody, Cd49f antibody, ITGA6 antibody, inta6 antibody, im:6897425 antibody, itga6 antibody, si:dkey-32o22.1 antibody, wu:fb80g02 antibody, LOC100221694 antibody, si:dkey-18j14.1 antibody, wu:fl20e08 antibody, zgc:113088 antibody, integrin subunit alpha 6 antibody, integrin alpha 6 antibody, integrin subunit alpha 6 L homeolog antibody, integrin, alpha 6a antibody, integrin, alpha 6b antibody, ITGA6 antibody, Itga6 antibody, itga6.L antibody, itga6a antibody, itga6b antibody
    背景
    The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Function: Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Cellular Location: Cell membrane, Single-pass type I membrane protein. Tissue Location: Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines, they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney).Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
    分子量
    126606 Da
    基因ID
    3655, 9606
    UniProt
    P23229
    途径
    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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