ITGA6 抗体 (Isoform 2)
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Quick Overview for ITGA6 抗体 (Isoform 2) (ABIN357904)
抗原
See all ITGA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Isoform 2
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特异性
- This antibody detects ITGA6 (Isoform 2).
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交叉反应 （详细）
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Species reactivity (expected):Chicken.
Species reactivity (tested):Human. -
纯化方法
- Protein A Chromatography followed by peptide affinity purification.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S1064 of human ITGA6 isoform 2.
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亚型
- Ig Fraction
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anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibody
ITGA6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 适用: 人 FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 129CT49-6-5 unconjugated
anti-Integrin, alpha 6 (ITGA6) (Ser1064) antibodyITGA6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1082-1110), (C-Term) antibodyITGA6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18006 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1043-1072), (Isoform 2) antibodyITGA6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15309 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 625-866) antibodyITGA6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibody (APC)ITGA6 适用: 人, 小鼠, 犬, Cow, Pig, 绵羊, 马, 兔, Cat, Non-Human Primate FACS 宿主: 大鼠 Monoclonal GoH3 APC
anti-Integrin, alpha 6 (ITGA6) (N-Term) antibodyITGA6 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 适用: 人, 小鼠, 犬, Pig, 绵羊, Cynomolgus FACS, IP, IHC (fro) 宿主: 大鼠 Monoclonal NKI-GoH3 unconjugated
anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibodyITGA6 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, 马, Hamster, 豚鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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别名
- CD49f / ITGA6
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背景
- The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Function: Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Cellular Location: Cell membrane, Single-pass type I membrane protein. Tissue Location: Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines, they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney).Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
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分子量
- 126606 Da
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基因ID
- 3655, 9606
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UniProt
- P23229
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途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
抗原
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