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ITGA6 抗体 (Isoform 2)

This anti-ITGA6 antibody is a 兔 多克隆 antibody detecting ITGA6 in WB, IF, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN357904
发货至: 中国

Quick Overview for ITGA6 抗体 (Isoform 2) (ABIN357904)

抗原

See all ITGA6 抗体
ITGA6 (Integrin, alpha 6 (ITGA6))

适用

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宿主

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克隆类型

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多克隆

标记

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This ITGA6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    Isoform 2

    特异性

    This antibody detects ITGA6 (Isoform 2).

    交叉反应 (详细)

    Species reactivity (expected):Chicken.
    Species reactivity (tested):Human.

    纯化方法

    Protein A Chromatography followed by peptide affinity purification.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S1064 of human ITGA6 isoform 2.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    ITGA6 (Integrin, alpha 6 (ITGA6))

    别名

    CD49f / ITGA6

    背景

    The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Function: Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Cellular Location: Cell membrane, Single-pass type I membrane protein. Tissue Location: Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines, they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney).Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6

    分子量

    126606 Da

    基因ID

    3655, 9606

    UniProt

    P23229

    途径

    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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