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PAPSS1 抗体 (C-Term)

PAPSS1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357814
发货至: 中国
  • 抗原 See all PAPSS1 抗体
    PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))
    抗原表位
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 24
    • 3
    • 2
    宿主
    • 21
    • 3
    克隆类型
    • 22
    • 2
    多克隆
    标记
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAPSS1 antibody is un-conjugated
    应用范围
    • 15
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects PAPSS1 (C-term).
    纯化方法
    Purified
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PAPSS1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PAPSS1 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))
    别名
    PAPSS1 (PAPSS1 产品)
    别名
    ATPSK1 antibody, PAPSS antibody, SK1 antibody, AI325286 antibody, Asapk antibody, papss1 antibody, MGC82588 antibody, atpsk1 antibody, papss antibody, sk1 antibody, PAPSS1 antibody, wu:fc43e12 antibody, zgc:194984 antibody, zgc:194985 antibody, CG8363 antibody, DmPAPSS antibody, Dmel\\CG8363 antibody, PAPS antibody, Paps antibody, l(3)76BDn antibody, paps antibody, 3'-phosphoadenosine 5'-phosphosulfate synthase 1 antibody, bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 antibody, bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 antibody, PAPS synthetase antibody, PAPSS1 antibody, Papss1 antibody, papss1 antibody, papss1.L antibody, LOC100543301 antibody, LOC100637112 antibody, Papss antibody
    背景
    Sulfotransferase (SULT) enzymes catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase (PAPSS) catalyzes the biosynthesis of PAPS which serves as the universal sulfonate donor compound for all sulfotransferase reactions. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (603005). Bifunctional PAPSS1 is comprised of an N-terminal APS kinase domain, and a C-terminal ATP sulfurylase domain. Full-length protein has significantly less APS kinase activity than the N-terminal fragment, suggesting that the C-terminal domain exerts a regulatory role on the N-terminal APS kinase activity. In humans there are two major isoforms: PAPSS1 and PAPSS2. In brain and skin PAPSS1 is the major isoform, whereas in liver, cartilage and adrenal glands PAPSS2 isoform expression dominates. The predicted 623-amino acid protein is 98 % identical to mouse PAPS synthase. The N-terminal 268-amino acid region of human PAPS synthase resembles APS kinases from other organisms and contains 3 conserved nucleotide-binding motifs.Synonyms: ATPSK1, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, PAPSS, PAPSS 1, SK1, Sulfurylase kinase 1
    分子量
    70833 Da
    基因ID
    9061, 9606
    UniProt
    O43252
    途径
    Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process
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