GPLD1 抗体 (C-Term)
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Quick Overview for GPLD1 抗体 (C-Term) (ABIN357724)
抗原
See all GPLD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects GPLD1 (C-term).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GPLD1.
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亚型
- Ig Fraction
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anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 496-840) antibody
GPLD1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 24-160) antibodyGPLD1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) antibodyGPLD1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 310-565) antibodyGPLD1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (Internal Region) antibodyGPLD1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 1-176) antibodyGPLD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1) (AA 679-709), (C-Term) antibodyGPLD1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04854 unconjugated
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应用备注
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ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- GPLD1 (Glycosylphosphatidylinositol Specific phospholipase D1 (GPLD1))
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别名
- GPLD1 / GPI-PLD
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背景
- GPLD1 is expressed in numerous tissues and cells and specifically cleaves GPI-anchored proteins. Liver has the highest level of GPI-PLD expression and is the primary organ contributing to GPLD1 in the serum. GPLD1 is abundant in serum in which it associates with polipoproteins AI and AIV. Increased serum GPLD1 is associated with insulin resistance and elevated serum triglycerides. Many surface proteins are attached to eukaryotic cell membranes via glycosylphosphatidylinositol (GPI) anchors that are covalently bound to the C-terminus of the protein and cleavage of the GPI moiety by GPLD1, only enzyme known that cleavage GPI anchor, may represent a means of regulating attachment of these proteins to the cell surface, or alternatively, their release into the extracellular environment.Synonyms: GPI-specific phospholipase D, Glycoprotein phospholipase D, Glycosyl-phosphatidylinositol-specific phospholipase D, PI-G PLD, PIGPLD1, Phosphatidylinositol-glycan-specific phospholipase D
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分子量
- 92666 Da
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基因ID
- 2822, 9606
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UniProt
- P80108
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途径
- Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
抗原
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