FNTA 抗体 (Middle Region)
Quick Overview for FNTA 抗体 (Middle Region) (ABIN357717)
抗原
See all FNTA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody detects FNTA (Center).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human FNTA.
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亚型
- Ig Fraction
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anti-Farnesyltransferase, CAAX Box, alpha (FNTA) (AA 51-366) antibody
FNTA 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Farnesyltransferase, CAAX Box, alpha (FNTA) (AA 1-214) antibodyFNTA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Farnesyltransferase, CAAX Box, alpha (FNTA) antibodyFNTA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Farnesyltransferase, CAAX Box, alpha (FNTA) (AA 330-360), (C-Term) antibodyFNTA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4794 unconjugated
anti-Farnesyltransferase, CAAX Box, alpha (FNTA) (N-Term) antibodyFNTA 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Farnesyltransferase, CAAX Box, alpha (FNTA) (C-Term) antibodyFNTA 适用: 人, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Farnesyltransferase, CAAX Box, alpha (FNTA) (AA 280-379) antibodyFNTA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Farnesyltransferase, CAAX Box, alpha (FNTA) (N-Term) antibodyFNTA 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
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别名
- FNTA
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背景
- FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.Synonyms: CAAX farnesyltransferase subunit alpha, FTase-alpha, GGTase-I-alpha, Protein farnesyltransferase / geranylgeranyltransferase type-1 subunit alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha
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分子量
- 44408 Da
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基因ID
- 2339, 9606
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UniProt
- P49354
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途径
- Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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