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FDFT1 抗体 (Middle Region)

This anti-FDFT1 antibody is a 兔 多克隆 antibody detecting FDFT1 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN357712
发货至: 中国

Quick Overview for FDFT1 抗体 (Middle Region) (ABIN357712)

抗原

See all FDFT1 抗体
FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

适用

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宿主

  • 73
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克隆类型

  • 70
  • 11
多克隆

标记

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This FDFT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Middle Region

    特异性

    This antibody detects FDFT1 (Center).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human FDFT1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/50-1/200. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

    别名

    Squalene Synthetase

    背景

    FDFT1 catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.Synonyms: FDFT1, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, SQS, SS

    分子量

    48115 Da

    基因ID

    2222, 5874

    UniProt

    P37268

    途径

    Regulation of Lipid Metabolism by PPARalpha
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