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USP13 抗体 (Middle Region)

This anti-USP13 antibody is a 兔 多克隆 antibody detecting USP13 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357545
发货至: 中国

Quick Overview for USP13 抗体 (Middle Region) (ABIN357545)

抗原

See all USP13 抗体
USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

适用

  • 53
  • 32
  • 5
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  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 52
  • 4

克隆类型

  • 43
  • 13
多克隆

标记

  • 32
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
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  • 2
This USP13 antibody is un-conjugated

应用范围

  • 41
  • 24
  • 21
  • 8
  • 6
  • 4
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  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 7
    • 5
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Middle Region

    特异性

    This antibody is specific to USP13 (Center).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human USP13.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))

    别名

    USP13

    背景

    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 13, ISOT-3, ISOT3, Isopeptidase T-3, Ubiquitin carboxyl-terminal hydrolase 13, Ubiquitin thioesterase 13, Ubiquitin-specific-processing protease 13

    分子量

    97299 Da

    基因ID

    8975, 5874

    UniProt

    Q92995

    途径

    SARS-CoV-2 Protein Interactome
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