UBE2D1 抗体 (C-Term)
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北京 101111
Quick Overview for UBE2D1 抗体 (C-Term) (ABIN357485)
抗原
See all UBE2D1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is specific to UBE2D1/SFT (C-term).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human UBE2D1.
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亚型
- Ig Fraction
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anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-94) antibody
UBE2D1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C6 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) antibodyUBE2D1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-147) antibodyUBE2D1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (C-Term) antibodyUBE2D1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 1-95) antibodyUBE2D1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C6 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 111-140), (C-Term) antibodyUBE2D1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04139 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (Middle Region) antibodyUBE2D1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, Pig, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) antibodyUBE2D1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB1900 unconjugated Recombinant Antibody
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) (AA 91-140) antibodyUBE2D1 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 马, Pig, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1) antibodyUBE2D1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
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别名
- UBE2D1 / SFT
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背景
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.Synonyms: E2(17)KB 1, UBC4/5 homolog, UBCH5, UBCH5A, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-protein ligase D1
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分子量
- 16602 Da
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基因ID
- 7321, 5874
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UniProt
- P51668
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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