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UBE2D1 抗体 (C-Term)

This anti-UBE2D1 antibody is a 兔 多克隆 antibody detecting UBE2D1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357485
发货至: 中国

Quick Overview for UBE2D1 抗体 (C-Term) (ABIN357485)

抗原

See all UBE2D1 抗体
UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This UBE2D1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody is specific to UBE2D1/SFT (C-term).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human UBE2D1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

    别名

    UBE2D1 / SFT

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.Synonyms: E2(17)KB 1, UBC4/5 homolog, UBCH5, UBCH5A, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-protein ligase D1

    分子量

    16602 Da

    基因ID

    7321, 5874

    UniProt

    P51668

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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