SOX2 抗体 (N-Term)
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Quick Overview for SOX2 抗体 (N-Term) (ABIN357437)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects SOX2 at N-term.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Zebrafish.
Species reactivity (tested):Human. -
纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- This SOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97~126 amino selected from the N-terminal region of human SOX2.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50. Immunofluorescence: 1/10-1/50. Flow Cytometry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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别名
- SOX2
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背景
- The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.Synonyms: ANOP3, MCOPS3, SRY (sex determining region Y)-box 2, SRY-box 2, SRY-related HMG-box gene 2, Transcription factor SOX-2
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分子量
- 34310 Da (based on amino acid sequence). Theoretical pI: 9.74.
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基因ID
- 6657, 9606
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UniProt
- P48431
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途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
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