BMPR1A 抗体 (N-Term)
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北京 101111
Quick Overview for BMPR1A 抗体 (N-Term) (ABIN357374)
抗原
See all BMPR1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects BMPR1A at N-term.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BMPR1A.
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亚型
- Ig Fraction
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anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 179-378) antibody
BMPR1A 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B7B2 unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 101-200) antibodyBMPR1A 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 30-60), (N-Term) antibodyBMPR1A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01766 unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 27-42), (Extracellular) antibodyBMPR1A 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 30-60) antibodyBMPR1A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (N-Term) antibodyBMPR1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 177-532) antibodyBMPR1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 24-200) antibodyBMPR1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 166-195) antibodyBMPR1A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB05263 unconjugated
anti-Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 166-196), (C-Term) antibodyBMPR1A 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01772 unconjugated
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应用备注
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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别名
- CD292 / BMPR1A
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背景
- The bone morphogenetic protein (BMP) receptors belong to a family of transmembrane serine/threonine kinases including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. Both activins and TGF-beta transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMP receptors are highly expressed in bone, skeletal muscle, heart and liver tissue. BMPRs play a crucial role during development as mutations or deletions to the BMPR genes can cause juvenile polyposis, disrupt normal dorsal/ventral patterning during limb development, and may be a factor in the progession of Cowden-like syndrome. Germline mutations in the BMPR2 gene encoding bone morphogenetic protein (BMP) type II receptor (BMPR-II) have been reported in patients with primary pulmonary hypertension (PPH).Synonyms: ACVRLK3, ALK-3, ALK3, Activin receptor-like kinase 3, Bone morphogenetic protein receptor type-1A, SKR5, Serine/threonine-protein kinase receptor R5
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分子量
- 60201 Da
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基因ID
- 657, 5874
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UniProt
- P36894
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途径
- Stem Cell Maintenance
抗原
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