URI1 抗体 (C-Term)
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Quick Overview for URI1 抗体 (C-Term) (ABIN357308)
抗原
See all URI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human RMP.
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亚型
- Ig Fraction
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应用备注
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ELISA 1: 1,000. Western blot 1: 250 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- URI1 (URI1, Prefoldin-Like Chaperone (URI1))
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别名
- RMP
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背景
- The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.Synonyms: C19orf2, NNX3, Protein NNX3, RNA polymerase II subunit 5-mediating protein, RPB5-mediating protein, URI, Unconventional prefoldin RPB5 interactor
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分子量
- 56764 Da
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基因ID
- 8725, 9606
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UniProt
- O94763
抗原
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