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SIGLEC9 抗体 (C-Term)

This anti-SIGLEC9 antibody is a 兔 多克隆 antibody detecting SIGLEC9 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357151
发货至: 中国

Quick Overview for SIGLEC9 抗体 (C-Term) (ABIN357151)

抗原

See all SIGLEC9 抗体
SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

适用

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人, 小鼠

宿主

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克隆类型

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  • 1
多克隆

标记

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This SIGLEC9 antibody is un-conjugated

应用范围

  • 66
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects SIGLEC9 at C-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SIGLEC9.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

    别名

    CD329 / SIGLEC9

    背景

    SIGLEC9 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. This protein is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). It is found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary, adrenal gland, colon, trachea, cerebellum, testis, small intestine and spinal cordon. SIGLEC9 contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.Synonyms: CDw329, FOAP-9, OBBP-like, SIGLEC-9, Sialic acid-binding Ig-like lectin 9

    分子量

    50081 Da

    基因ID

    27180

    NCBI登录号

    NP_055256

    UniProt

    Q9Y336
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