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GJA8 抗体 (C-Term)

This anti-GJA8 antibody is a 兔 多克隆 antibody detecting GJA8 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN357099
发货至: 中国

Quick Overview for GJA8 抗体 (C-Term) (ABIN357099)

抗原

See all GJA8 抗体
GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This GJA8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects Connexin 50 (GJA8) at C-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GJA8.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

    别名

    GJA8 / Cx50

    背景

    GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.Synonyms: Connexin-50, Gap junction alpha-8 protein, Lens fiber protein MP70

    分子量

    48097 Da

    基因ID

    2703, 9606

    UniProt

    P48165
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