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Cx40/GJA5 抗体 (N-Term)

This anti-Cx40/GJA5 antibody is a 兔 多克隆 antibody detecting Cx40/GJA5 in WB 和 EIA. Suitable for 人.
产品编号 ABIN357093
发货至: 中国

Quick Overview for Cx40/GJA5 抗体 (N-Term) (ABIN357093)

抗原

See all Cx40/GJA5 (GJA5) 抗体
Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

适用

  • 42
  • 16
  • 9
  • 3
  • 2
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  • 1
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宿主

  • 48
  • 2

克隆类型

  • 48
  • 2
多克隆

标记

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  • 2
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  • 1
  • 1
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  • 1
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This Cx40/GJA5 antibody is un-conjugated

应用范围

  • 34
  • 22
  • 22
  • 12
  • 7
  • 6
  • 5
  • 3
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  • 1
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 9
    • 7
    • 6
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    • 3
    • 3
    • 2
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    • 1
    • 1
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    N-Term

    特异性

    This antibody detects Connexin 40 (GJA5) at N-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GJA5.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

    别名

    GJA5 / Cx40

    背景

    Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.Synonyms: Connexin-40, Gap junction alpha-5 protein

    分子量

    40249 Da

    基因ID

    2702, 9606

    UniProt

    P36382

    途径

    Cell-Cell Junction Organization
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