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Connexin 31 抗体 (C-Term)

This anti-Connexin 31 antibody is a 兔 多克隆 antibody detecting Connexin 31 in IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN357088
发货至: 中国

Quick Overview for Connexin 31 抗体 (C-Term) (ABIN357088)

抗原

See all Connexin 31 (GJB3) 抗体
Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

适用

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宿主

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克隆类型

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多克隆

标记

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This Connexin 31 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects Connexin 31 (GJB3) at C-term.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GJB3.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

    别名

    GJB3 / Cx31

    背景

    Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.Synonyms: Connexin-31, Gap junction beta-3 protein

    分子量

    30818 Da

    基因ID

    2707, 9606

    UniProt

    O75712

    途径

    Sensory Perception of Sound
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