P-Cadherin 抗体 (C-Term)
Quick Overview for P-Cadherin 抗体 (C-Term) (ABIN357039)
抗原
See all P-Cadherin (CDH3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects CDH3 at C-term.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Then the antibody is purified by peptide affinity purification.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CDH3.
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亚型
- Ig Fraction
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应用备注
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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: "Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 7, pp. 666-74, (2013) (PubMed).
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: "Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 7, pp. 666-74, (2013) (PubMed).
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- P-Cadherin (CDH3)
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别名
- Cadherin-3
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背景
- CDH3 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in the gene encoding CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.Synonyms: CDH3, CDHP, Cadherin P, P-Cadherin, Placental cadherin
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分子量
- 91418 Da
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基因ID
- 1001, 9606
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UniProt
- P22223
抗原
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