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PYGM 抗体 (C-Term)

PYGM 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356948
发货至: 中国
  • 抗原 See all PYGM 抗体
    PYGM (Phosphorylase, Glycogen, Muscle (PYGM))
    抗原表位
    • 15
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    C-Term
    适用
    • 31
    • 22
    • 19
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 45
    • 6
    • 2
    克隆类型
    • 47
    • 6
    多克隆
    标记
    • 23
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PYGM antibody is un-conjugated
    应用范围
    • 44
    • 17
    • 17
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects PYGM at C-term.
    纯化方法
    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PYGM.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PYGM Primary Antibody
  • 应用备注
    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Hathout, Marathi, Rayavarapu, Zhang, Brown, Seol, Gordish-Dressman, Cirak, Bello, Nagaraju, Partridge, Hoffman, Takeda, Mah, Henricson, McDonald: "Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients." in: Human molecular genetics, Vol. 23, Issue 24, pp. 6458-69, (2015) (PubMed).

  • 抗原
    PYGM (Phosphorylase, Glycogen, Muscle (PYGM))
    别名
    Glycogen Phosphorylase Muscle Form (PYGM 产品)
    别名
    pygb antibody, im:7150327 antibody, zgc:110706 antibody, AI115133 antibody, PG antibody, Muscpho antibody, zgc:63642 antibody, phosphorylase, glycogen, muscle L homeolog antibody, glycogen phosphorylase, muscle associated antibody, phosphorylase, glycogen, muscle A antibody, glycogen phosphorylase, muscle form antibody, muscle glycogen phosphorylase antibody, phosphorylase, glycogen, muscle b antibody, pygm.L antibody, PYGM antibody, pygma antibody, THA_70 antibody, Pygm antibody, pygmb antibody
    背景
    PYGM catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5), also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.Synonyms: GPMM, Myophosphorylase, PYGM, Phosphorylase A, Phosphorylase B
    分子量
    97092 Da
    基因ID
    5837, 9606
    UniProt
    P11217
    途径
    Cellular Glucan Metabolic Process
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