PYGM 抗体 (C-Term)
Quick Overview for PYGM 抗体 (C-Term) (ABIN356948)
抗原
See all PYGM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects PYGM at C-term.
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纯化方法
- Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PYGM.
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亚型
- Ig Fraction
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应用备注
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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: "Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients." in: Human molecular genetics, Vol. 23, Issue 24, pp. 6458-69, (2015) (PubMed).
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: "Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients." in: Human molecular genetics, Vol. 23, Issue 24, pp. 6458-69, (2015) (PubMed).
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- PYGM (Phosphorylase, Glycogen, Muscle (PYGM))
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别名
- Glycogen Phosphorylase Muscle Form
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背景
- PYGM catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5), also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.Synonyms: GPMM, Myophosphorylase, PYGM, Phosphorylase A, Phosphorylase B
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分子量
- 97092 Da
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基因ID
- 5837, 9606
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UniProt
- P11217
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途径
- Cellular Glucan Metabolic Process
抗原
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