CDCA8 抗体 (Center)
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北京 101111
Quick Overview for CDCA8 抗体 (Center) (ABIN356941)
抗原
See all CDCA8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects CDCA8 at center.
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纯化方法
- Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CDCA8.
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亚型
- Ig Fraction
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应用备注
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ELISA 1: 1,000. Western blotting 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- CDCA8 (Cell Division Cycle Associated 8 (CDCA8))
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别名
- CDCA8 / Borealin
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背景
- CDCA8 is a component of the chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The CPC complex, a key regulator of mitosis, has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 may be required to direct the CPC to centromeric DNA.Synonyms: Cell division cycle-associated protein 8, Dasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein, hDasra-B
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分子量
- 31323 Da
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基因ID
- 55143, 9606
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UniProt
- Q53HL2
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途径
- Cell Division Cycle, M Phase
抗原
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