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Stanniocalcin 2 抗体 (N-Term)

This anti-Stanniocalcin 2 antibody is a 兔 多克隆 antibody detecting Stanniocalcin 2 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN356935
发货至: 中国

Quick Overview for Stanniocalcin 2 抗体 (N-Term) (ABIN356935)

抗原

See all Stanniocalcin 2 (STC2) 抗体
Stanniocalcin 2 (STC2)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Stanniocalcin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects STC2 at N-term.

    纯化方法

    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    KLH conjugated synthetic peptide selected from the N-terminal region of human STC2

    亚型

    Ig Fraction
  • 应用备注

    ELISA1: 1,000. Western blotting 1: 100 - 1: 500. Immunohistochemistry: 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Stanniocalcin 2 (STC2)

    别名

    Stanniocalcin 2 / STC2

    背景

    STC2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression is induced by estrogen and altered in some breast cancers.Synonyms: STC-2, STC-related protein, STCRP, Stanniocalcin-2, Stanniocalcin-related protein

    分子量

    33249 Da

    基因ID

    8614, 9606

    UniProt

    O76061

    途径

    Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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