TXN 抗体 (N-Term)
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北京 101111
Quick Overview for TXN 抗体 (N-Term) (ABIN356853)
抗原
See all TXN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody is specific to Thioredoxin (TRX) (N-term).
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- KLH conjugated synthetic peptide selected from the N-terminal region of Human TrX.
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亚型
- Ig Fraction
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anti-Thioredoxin (TXN) (AA 1-105) antibody
TXN 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Thioredoxin (TXN) (C-Term) antibodyTXN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 2-105) antibodyTXN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN 适用: 人 WB, IHC, ICC, IP, FACS 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN 适用: 人 WB 宿主: 小鼠 Monoclonal 3# unconjugated
anti-Thioredoxin (TXN) (AA 66-94), (C-Term) antibodyTXN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB42816 unconjugated
anti-Thioredoxin (TXN) (AA 51-105) antibodyTXN 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin (TXN) antibodyTXN 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Thioredoxin (TXN) antibodyTXN 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7270 unconjugated
anti-Thioredoxin (TXN) (AA 1-105) antibodyTXN 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- TXN (Thioredoxin (TXN))
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别名
- Thioredoxin / TRX1
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背景
- Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1.Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.Synonyms: ADF, ATL-derived factor, SASP, Surface-associated sulphydryl protein, TRDX, TRX, TXN
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分子量
- 11737 Da
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基因ID
- 7295, 9606
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UniProt
- P10599
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途径
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
抗原
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