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BCL2A1 抗体 (BH3 Domain, N-Term)

This anti-BCL2A1 antibody is a 兔 多克隆 antibody detecting BCL2A1 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN356809
发货至: 中国

Quick Overview for BCL2A1 抗体 (BH3 Domain, N-Term) (ABIN356809)

抗原

See all BCL2A1 抗体
BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BCL2A1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    BH3 Domain, N-Term

    特异性

    This antibody is specific to BCL2A1 (BH3 Domain).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody was developed against a synthetic peptide selected from the N-terminal region of human BCL2-related protein A1, within the BH3 domain.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

    背景

    Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.Synonyms: BCL2A1, BCL2L5, BFL1, Bcl-2-like protein 5, Bcl-2-related protein A1, GRS, HBPA1, Hemopoietic-specific early response protein, Protein BFL-1

    基因ID

    597, 9606

    UniProt

    Q16548
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