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Ubiquitin 抗体 (C-Term)

This anti-Ubiquitin antibody is a 兔 多克隆 antibody detecting Ubiquitin in WB, IF, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN356747
发货至: 中国

Quick Overview for Ubiquitin 抗体 (C-Term) (ABIN356747)

抗原

See all Ubiquitin (Ub) 抗体
Ubiquitin (Ub)

适用

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宿主

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克隆类型

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多克隆

标记

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This Ubiquitin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 44-73, C-Term

    特异性

    This antibody is specific to Ubiquitin (C-term).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide between 44~73 amino acids from the C-terminal region of Human Ubiquitin. Genename: UBC

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunofluorescence. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS, 0.09 % (W/V) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    Ubiquitin (Ub)

    别名

    Ubiquitin

    背景

    This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.Synonyms: Polyubiquitin-C, UBC

    分子量

    8.565 kDa

    基因ID

    7316

    NCBI登录号

    NP_066289

    UniProt

    P0CG48

    途径

    Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
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