PRDM2 抗体 (AA 245-573)
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Quick Overview for PRDM2 抗体 (AA 245-573) (ABIN356710)
抗原
See all PRDM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 245-573
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特异性
- This antibody also recognizes the isoform beta (Riz2) of PRDM2 (185 kDa)
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- Purified recombinant GST fusion protein encoding aa 245-573 of Rat Riz1. Genename: PRDM2
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western Blot.1/100-1/500. Immunohistochemistry: 1/100-1/500. Immunoprecipitation: 1 μg Pab/100 μg cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
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别名
- PRDM2
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背景
- PRDM2 is a 250-kD nuclear protein containing 8 zinc finger motifs. It contains an RB-binding motif that is related to that of the adenovirus E1A oncoprotein, RIZ also shares an antigenic epitope with the C terminus of E1A. It is expressed in human retinoblastoma cells and at low levels in all other human cell lines examined. Using fluorescence in situ hybridization, the PRDM2 gene has been mapped to 1p36. PRDM2 may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, skin, and lymphoid tumors.Synonyms: GATA-3-binding protein G3B, HUMHOXY1, KMT8, Lysine N-methyltransferase 8, MTB-ZF, MTE-binding protein, PR domain zinc finger protein 2, RIZ1, RIZ2, Retinoblastoma protein-interacting zinc finger protein
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基因ID
- 7799, 5874
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UniProt
- Q13029
抗原
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