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NCOR1 抗体 (N-Term)

This anti-NCOR1 antibody is a 兔 多克隆 antibody detecting NCOR1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN356671
发货至: 中国

Quick Overview for NCOR1 抗体 (N-Term) (ABIN356671)

抗原

See all NCOR1 抗体
NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This NCOR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody is specific to NCOR1 (N-term).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NCOR1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

    别名

    NCOR1

    背景

    NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.Synonyms: KIAA1047, N-CoR, N-CoR1, Nuclear receptor corepressor 1

    基因ID

    9611, 9606

    UniProt

    O75376

    途径

    Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process
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