HAT1 抗体 (N-Term)
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Quick Overview for HAT1 抗体 (N-Term) (ABIN356620)
抗原
See all HAT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 35-65, N-Term
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特异性
- This antibody is specific to Human HAT1 (N-term).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide between 35~65 amino acids from the N-terminal region of Human HAT1
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- HAT1 (Histone Acetyltransferase 1 (HAT1))
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别名
- HAT1
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背景
- Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.Synonyms: Histone acetyltransferase type B catalytic subunit
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基因ID
- 8520, 9606
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UniProt
- O14929
抗原
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