JMJD4 抗体 (C-Term)
Quick Overview for JMJD4 抗体 (C-Term) (ABIN356562)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody will recognize JMJD4 (C-term). It Cross reacts with Mouse (Predicted by 100 % Antigen Homology).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human JMJD4.
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亚型
- Ig Fraction
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anti-Jumonji Domain Containing 4 (JMJD4) (AA 72-121) antibody
JMJD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (C-Term) antibodyJMJD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (AA 1-463) antibodyJMJD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (AA 423-455), (C-Term) antibodyJMJD4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB10802 unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (C-Term) antibodyJMJD4 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (AA 1-30) antibodyJMJD4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 4 (JMJD4) (N-Term) antibodyJMJD4 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western Blot: 1/250-1/500. Immunohistochemistry: 1/10approx. 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- JMJD4 (Jumonji Domain Containing 4 (JMJD4))
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别名
- JMJD4
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背景
- Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: JmjC domain-containing protein 4, Jumonji domain-containing protein 4
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基因ID
- 65094, 9606
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UniProt
- Q9H9V9
抗原
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