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JMJD2D 抗体 (C-Term)

KDM4D 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356558
发货至: 中国
  • 抗原 See all JMJD2D (KDM4D) 抗体
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    抗原表位
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 34
    • 4
    • 2
    • 1
    • 1
    宿主
    • 34
    克隆类型
    • 34
    多克隆
    标记
    • 17
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This JMJD2D antibody is un-conjugated
    应用范围
    • 23
    • 18
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody will recognize JMJD2D (C-term).
    纯化方法
    Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human JMJD2D.
    亚型
    Ig Fraction
    Top Product
    Discover our top product KDM4D Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/250-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
    别名
    JMJD2D / KDM4D (KDM4D 产品)
    别名
    JMJD2D antibody, 4932416A15 antibody, Jmjd2d antibody, KDM4D antibody, lysine demethylase 4D antibody, lysine-specific demethylase 4D antibody, lysine (K)-specific demethylase 4D antibody, KDM4D antibody, LOC524768 antibody, Kdm4d antibody, LOC617971 antibody, LOC100067461 antibody, LOC698455 antibody, LOC100514356 antibody
    背景
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: JHDM3D, JmjC domain-containing histone demethylation protein 3D, Jumonji domain-containing protein 2D, Lysine-specific demethylase 4D
    基因ID
    55693
    NCBI登录号
    NP_060509
    UniProt
    Q6B0I6
    途径
    Warburg Effect
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