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KDM3B 抗体 (N-Term)

KDM3B 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356557
发货至: 中国
  • 抗原 See all KDM3B 抗体
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    抗原表位
    • 15
    • 9
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 59
    • 30
    • 22
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 59
    • 3
    克隆类型
    • 60
    • 2
    多克隆
    标记
    • 33
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KDM3B antibody is un-conjugated
    应用范围
    • 54
    • 29
    • 13
    • 13
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody will recognize JMJD1B (N-term).
    纯化方法
    Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human JMJD1B.
    亚型
    Ig Fraction
    Top Product
    Discover our top product KDM3B Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/250-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    别名
    JMJD1B / KDM3B (KDM3B 产品)
    别名
    KDM3B antibody, JMJD1B antibody, 5830462I21Rik antibody, JHDM2B antibody, Jmjd1b antibody, mKIAA1082 antibody, 5qNCA antibody, C5orf7 antibody, NET22 antibody, lysine demethylase 3B antibody, lysine (K)-specific demethylase 3B antibody, lysine-specific demethylase 3B antibody, KDM3B lysine (K)-specific demethylase 3B antibody, KDM3B antibody, LOC100540242 antibody, kdm3b antibody, Kdm3b antibody
    背景
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: 5qNCA, C5orf7, JHDM2B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, KIAA1082, Lysine-specific demethylase 3B, Nuclear protein 5qNCA
    基因ID
    51780, 9606
    UniProt
    Q7LBC6
    途径
    Warburg Effect
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