KDM3B 抗体 (N-Term)
Quick Overview for KDM3B 抗体 (N-Term) (ABIN356557)
抗原
See all KDM3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody will recognize JMJD1B (N-term).
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纯化方法
- Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human JMJD1B.
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亚型
- Ig Fraction
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anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1059-1283) antibody
KDM3B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1601-1761) antibodyKDM3B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1-759) antibodyKDM3B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (Internal Region) antibodyKDM3B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1691-1740) antibodyKDM3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 小鸡, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (C-Term) antibodyKDM3B 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 非洲爪蟾, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 869-897) antibodyKDM3B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14344 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1328-1358), (C-Term) antibodyKDM3B 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal RB14629 unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 1335-1358), (C-Term) antibodyKDM3B 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 3B (KDM3B) (AA 876-905), (Middle Region) antibodyKDM3B 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western Blot: 1/250-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
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别名
- JMJD1B / KDM3B
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背景
- Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: 5qNCA, C5orf7, JHDM2B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, KIAA1082, Lysine-specific demethylase 3B, Nuclear protein 5qNCA
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基因ID
- 51780, 9606
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UniProt
- Q7LBC6
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途径
- Warburg Effect
抗原
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