Thyroglobulin 抗体
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Quick Overview for Thyroglobulin 抗体 (ABIN356463)
抗原
See all Thyroglobulin (TG) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
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This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of Tg in metastatic lesion establishes thyroid origin of tumor.
Cellular Localization: Cytoplasmic. -
纯化方法
- Purified
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免疫原
- Purified human Thyroglobulin.
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亚型
- IgG
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应用备注
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Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100 using streptavidinapprox. biotin system orpolymer system. Immunofluorescence. Recommended Positive Control: Human thyroid.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Thyroglobulin (TG)
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背景
- Thyroglobulin (Tg) is a 660 kDa dimeric protein produced by and used by entirely within thyroid gland. Tg is used by the thyroid gland to produce the thyroid hormone thyroxine (T4) and triiodothyronine (T3). Tg is produced by the thyroid epithelial cells, called thyrocytes, which form spherical follicles. Tg is stored in the follicle lumen. Tg levels in the blood can be used as markers for certain kind of thyroid cancer. Tg levels are also elevated in Graves disease.Synonyms: TGN, Thyreoglobulin
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基因ID
- 7038
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NCBI登录号
- NP_003226
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UniProt
- P01266
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途径
- Thyroid Hormone Synthesis
抗原
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