EPHX2 抗体 (Internal Region)
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Quick Overview for EPHX2 抗体 (Internal Region) (ABIN356443)
抗原
See all EPHX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts with Soluble Epoxide Hydrolase (EPHX2).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide - KLH conjugated corresponding to internal domain of Human EPHX2.
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亚型
- IgG
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应用备注
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Immunohistochemistry on Paraffin Embedded Tissues: 20 μg/mL. This EPHX2 antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody LS-D1, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- EPHX2 (Epoxide Hydrolase 2, Cytoplasmic (EPHX2))
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别名
- Epoxide Hydrolase 2 / EPHX2
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背景
- Soluble Epoxide Hydrolase (sEH) also known as cytosolic Epoxide Hydrolase is a phase I xenobiotic-metabolizing enzyme that converts epoxyeicosatrienoic acids (EETs) into their corresponding dihydroxyeicosatrienoic acids (DHETs). EETs are thought to be involved in vascular tone, ion channel regulation, mitogenesis and cell signaling. DHETs have, in general, less biological activity then EETs and are more readily excreted, thus hydration of EETs by sEH maybe a means of attenuating or eliminating their activity. sEHs have been identified in many tissues including liver, kidney, adrenal, pancreatic islets, gi tract and vascular smooth muscle.Synonyms: CEH, Cytosolic epoxide hydrolase, Epoxide hydratase, SEH, Soluble epoxide hydrolase
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基因ID
- 2053
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NCBI登录号
- NP_001970
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UniProt
- P34913
抗原
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