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S100A1 抗体 (FITC)

This anti-S100A1 antibody is a 小鼠 单克隆 antibody detecting S100A1 in IF, FACS 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 Cow.
产品编号 ABIN356321
发货至: 中国

Quick Overview for S100A1 抗体 (FITC) (ABIN356321)

抗原

See all S100A1 抗体
S100A1 (S100 Calcium Binding Protein A1 (S100A1))

适用

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人, 小鼠, 大鼠, Cow

宿主

  • 79
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  • 2
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  • 1
小鼠

克隆类型

  • 73
  • 69
单克隆

标记

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This S100A1 antibody is conjugated to FITC

应用范围

  • 83
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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

S100217
  • 特异性

    This antibody stains schwannoma, ependymomas, astrogliomas, almost all benign and malignant melanoma and their metasis.
    Cellular Localization: Cytoplasmic.

    交叉反应 (详细)

    Species reactivity (tested):Human, Monkey, Bovine, Rat and Mouse

    产品特性

    Synonyms: S100 Calcium binding protein, S-100 protein, S100A, S100B, S-100 protein alpha chain,S-100 protein beta chain, Astrocyte Marker, S-100 protein alpha subunit, S-100 proteinbeta subunit, S100 Alpha, S100 Beta

    纯化方法

    Protein A Chromatography.

    免疫原

    Purified bovine S100 protein. Remarks: Molecular weight of antigen: ~22 kDa.

    亚型

    IgG1
  • 应用备注

    Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS, pH 7.4, 0.05 % Sodium Azide, 1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Shelf life: One year from despatch.

    有效期

    12 months
  • 抗原

    S100A1 (S100 Calcium Binding Protein A1 (S100A1))

    别名

    S100A1

    背景

    S100 protein is a type of low molecular weight protein found in vertebrates characterized by two calcium binding sites of the helix-loop-helix ("EF-hand type") conformation. There are at least 21 different types of S100 proteins. The name is derived from the fact that the protein is 100 % Soluble in ammonium sulfate at neutral pH . Most S100 proteins are homodimeric, consisting of two identical polypeptides held together by non-covalent bonds. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. Although S100 proteins are structurally similar to calmodulin, they differ in that they are cell-specific, expressed in particular cells at different levels depending on environmental factors. To contrast, calmodulin is a ubiquitous and universal intracellular Ca++ receptor widely expressed in many cells.S-100 is normally present in cells derived from the neural crest (Schwann cells, melanocytes, and glia cells), chondrocyte, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. It may be present in some breast epithelial cells.Synonyms: Astrocyte Marker, S-100 protein, S-100 protein alpha chain, S-100 protein alpha subunit, S-100 protein beta chain, S-100 protein beta subunit, S100 Alpha, S100 Beta, S100 Calcium binding protein, S100A, S100B

    基因ID

    528735

    UniProt

    P02639

    途径

    Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
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