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Fibrillin 1 抗体

FBN1 适用: 人, Cow WB, IHC (fro), IF, IEM 宿主: 小鼠 Monoclonal 11C1-3 unconjugated
产品编号 ABIN356183
发货至: 中国
  • 抗原 See all Fibrillin 1 (FBN1) 抗体
    Fibrillin 1 (FBN1)
    适用
    • 57
    • 30
    • 21
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, Cow
    宿主
    • 69
    • 11
    • 1
    小鼠
    克隆类型
    • 71
    • 10
    单克隆
    标记
    • 41
    • 16
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Fibrillin 1 antibody is un-conjugated
    应用范围
    • 55
    • 30
    • 30
    • 15
    • 14
    • 13
    • 13
    • 13
    • 11
    • 9
    • 5
    • 3
    • 1
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    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunoelectron Microscopy (IEM)
    特异性
    This antibody recognises Fibrillin (Mr 350 kDa).
    产品特性
    Synonyms: FBN1, FBN
    纯化方法
    Purified
    免疫原
    Microfibrils from zonular apparatus of bovine eye.
    克隆位点
    11C1-3
    亚型
    IgG1
    Top Product
    Discover our top product FBN1 Primary Antibody
  • 应用备注
    Immunohistochemistry: 1/50-1/100 (30-60 min at RT). (See Ref.2)Immunofluorescence. (See Ref.2)Western blotting: < / = 1 μg/mL (See Ref.2)Electron Microscopic Immunolocalization. (See Ref.2)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    Fibrillin 1 (FBN1)
    别名
    Fibrillin-1 (FBN1 产品)
    别名
    FBN1 antibody, ACMICD antibody, ECTOL1 antibody, FBN antibody, GPHYSD2 antibody, MASS antibody, MFS1 antibody, OCTD antibody, SGS antibody, SSKS antibody, WMS antibody, WMS2 antibody, AI536462 antibody, B430209H23 antibody, Fib-1 antibody, Tsk antibody, fibrillin 1 antibody, FBN1 antibody, Fbn1 antibody
    背景
    The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.(Ref.1) In Immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues.(Ref.2,3) There is an aberrant expression of fibrillin in Marfan syndrome.(Ref.4)Synonyms: FBN, FBN1
    基因ID
    2200
    UniProt
    P35555
    途径
    Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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