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Fibrillin 1 抗体

This anti-Fibrillin 1 antibody is a 小鼠 单克隆 antibody detecting Fibrillin 1 in WB, IHC (fro), IF 和 IEM. Suitable for 人 和 Cow.
产品编号 ABIN356183
发货至: 中国

Quick Overview for Fibrillin 1 抗体 (ABIN356183)

抗原

See all Fibrillin 1 (FBN1) 抗体
Fibrillin 1 (FBN1)

适用

  • 76
  • 38
  • 27
  • 10
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
人, Cow

宿主

  • 99
  • 12
  • 1
小鼠

克隆类型

  • 101
  • 11
单克隆

标记

  • 62
  • 19
  • 12
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Fibrillin 1 antibody is un-conjugated

应用范围

  • 80
  • 50
  • 38
  • 33
  • 24
  • 18
  • 14
  • 14
  • 13
  • 13
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunoelectron Microscopy (IEM)

克隆位点

11C1-3
  • 特异性

    This antibody recognises Fibrillin (Mr 350 kDa).

    产品特性

    Synonyms: FBN1, FBN

    纯化方法

    Purified

    免疫原

    Microfibrils from zonular apparatus of bovine eye.

    亚型

    IgG1
  • 应用备注

    Immunohistochemistry: 1/50-1/100 (30-60 min at RT). (See Ref.2)Immunofluorescence. (See Ref.2)Western blotting: < / = 1 μg/mL (See Ref.2)Electron Microscopic Immunolocalization. (See Ref.2)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
    Shelf life: One year from despatch.

    有效期

    12 months
  • 抗原

    Fibrillin 1 (FBN1)

    别名

    Fibrillin-1

    背景

    The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.(Ref.1) In Immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues.(Ref.2,3) There is an aberrant expression of fibrillin in Marfan syndrome.(Ref.4)Synonyms: FBN, FBN1

    基因ID

    2200

    UniProt

    P35555

    途径

    Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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