Optimal working dilutions should be determined experimentally by the investigator.
限制
仅限研究用
状态
Liquid
储存条件
-20 °C
抗原
PERP
(TP53 Apoptosis Effector (PERP))
别名
PERP/TP53 Apoptosis Effector Protein
背景
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. PERP (TP53 Apoptosis Effector) is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.