Factor Inhibiting HIF-1 Antibody (Extracellular Domain), (N-Term) 抗体
The 兔 多克隆 anti-Factor Inhibiting HIF-1 Antibody antibody is suitable to detect Factor Inhibiting HIF-1 Antibody in samples from 小鼠 和 大鼠. It has been validated for ICC, IHC 和 WB.
产品编号 ABIN356096
发货至:
中国
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Our Local Distributor
中国
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北京 101111
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Quick Overview for Factor Inhibiting HIF-1 Antibody (Extracellular Domain), (N-Term) 抗体 (ABIN356096)
抗原
Factor Inhibiting HIF-1 Antibody
适用
小鼠, 大鼠
宿主
兔
克隆类型
多克隆
应用范围
Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
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抗原表位
- Extracellular Domain, N-Term
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Aff - Purified
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免疫原
- Synthetic peptide (Rat) from the N-terminal extracellular domain conjugated to immunogenic carrier protein.
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- -20 °C
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- Factor Inhibiting HIF-1 Antibody
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物质类
- Antibody
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背景
- Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.
抗原
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