DEFA5 抗体 (cleaved)
The 小鼠 单克隆 anti-DEFA5 antibody is suitable to detect DEFA5 in samples from 人. It has been validated for IHC.
产品编号 ABIN356090
发货至:
中国
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Quick Overview for DEFA5 抗体 (cleaved) (ABIN356090)
抗原
See all DEFA5 抗体
DEFA5
(Defensin, alpha 5, Paneth Cell-Specific (DEFA5))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This DEFA5 antibody is un-conjugated
应用范围
Immunohistochemistry (IHC)
克隆位点
8C8
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抗原表位
- cleaved
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交叉反应
- 人
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纯化方法
- Aff - Purified
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免疫原
- Full-length proHD5 protein. [Swiss-Prot# Q01523] The propeptide is the full-length protein. In the mature form, it is cleaved at residue 63 (alanine).
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亚型
- IgG
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anti-Defensin, alpha 5, Paneth Cell-Specific (DEFA5) (AA 1-94) antibody
DEFA5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 5, Paneth Cell-Specific (DEFA5) (AA 20-94) antibodyDEFA5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- -20 °C
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- DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))
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别名
- Defensin 5
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背景
- Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. Alpha-defensins 5 and 6 probably contribute to innate defense of the GI mucosal surface by protecting against microbial invasion in states of intestinal inflammation.
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UniProt
- Q01523
抗原
-
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