Vesicle-Associated Membrane Protein 2-Like (LOC102558953) (AA 10-60) 抗体
LOC102558953
适用: 人
WB, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- Vesicle-Associated Membrane Protein 2-Like (LOC102558953)
- 抗原表位
- AA 10-60
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Rabbit antibody to VAMP 2 1 (10-60)
- 特异性
- Specific for VAMP2 and VAMP1.
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 （详细）
- Other species not yet tested.
- 纯化方法
- IgG
- 免疫原
- A synthetic peptide from AA 10-60 of human VAMP2 conjugated to blue carrier protein was used as the antigen. The VAMP2 peptide shares 93% shared identity with VAMP1. The peptide is homologous in many other species including rat mouse and xenopus.
- 亚型
- IgG
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- 应用备注
- IHC WB. A working concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
- 注意事项
- Avoid freeze and thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- 有效期
- 12 months
-
- 抗原
- Vesicle-Associated Membrane Protein 2-Like (LOC102558953)
- 别名
- VAMP 2 1
- 背景
- The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs syntaxins and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin synaptosomal-associated protein 25 kD and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. FUNCTION: Involved in the targeting and/or fusion of transport vesicles to their target membrane. SUBCELLULAR LOCATION: Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane, Single-pass type IV membrane protein. Cell junction synapse synaptosome. Note: Neuronal synaptic vesicles.
- UniProt
- P63027
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