Vesicle-Associated Membrane Protein 2-Like (LOC102558953) (AA 10-60) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in IHC 和 WB. Suitable for 人.
Quick Overview for Vesicle-Associated Membrane Protein 2-Like (LOC102558953) (AA 10-60) 抗体 (ABIN7698533)
抗原
Vesicle-Associated Membrane Protein 2-Like (LOC102558953)
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
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抗原表位
- AA 10-60
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原理
- Rabbit antibody to VAMP 2 1 (10-60)
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特异性
- Specific for VAMP2 and VAMP1.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from AA 10-60 of human VAMP2 conjugated to blue carrier protein was used as the antigen. The VAMP2 peptide shares 93% shared identity with VAMP1. The peptide is homologous in many other species including rat mouse and xenopus.
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亚型
- IgG
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应用备注
- IHC WB. A working concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- Vesicle-Associated Membrane Protein 2-Like (LOC102558953)
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别名
- VAMP 2 1
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背景
- The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs syntaxins and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin synaptosomal-associated protein 25 kD and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. FUNCTION: Involved in the targeting and/or fusion of transport vesicles to their target membrane. SUBCELLULAR LOCATION: Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane, Single-pass type IV membrane protein. Cell junction synapse synaptosome. Note: Neuronal synaptic vesicles.
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UniProt
- P63027
抗原
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