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VPS36 抗体 (Internal Region)

This anti-VPS36 antibody is a 兔 多克隆 antibody detecting VPS36 in IHC 和 WB. Suitable for 小鼠.
产品编号 ABIN351331
发货至: 中国

Quick Overview for VPS36 抗体 (Internal Region) (ABIN351331)

抗原

See all VPS36 抗体
VPS36 (Vacuolar Protein Sorting 36 (VPS36))

适用

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小鼠

宿主

  • 17
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克隆类型

  • 19
多克隆

标记

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This VPS36 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 4
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    Internal Region

    原理

    Rabbit antibody to VPS36

    特异性

    Specific for VPS36.

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    A synthetic peptide from the internal region of mouse VPS36 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat.

    亚型

    IgG
  • 应用备注

    IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    VPS36 (Vacuolar Protein Sorting 36 (VPS36))

    别名

    VPS36

    背景

    FUNCTION: Component of the ESCRT-II complex which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation possibly via its interaction with ELL. SUBCELLULAR LOCATION: Cytoplasm. Late endosome. Nucleus. NoteL Colocalizes with ubiquitinated proteins on late endosomes.

    UniProt

    Q91XD6
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