VPS29 抗体 (C-Term)
Quick Overview for VPS29 抗体 (C-Term) (ABIN351326)
抗原
See all VPS29 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit antibody to VPS29
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特异性
- Specific for VPS29.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from the c-terminal region of mouse VPS29 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat human chicken zebra fish and xenopus.
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亚型
- IgG
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- VPS29 (Vacuolar Protein Sorting 29 (VPS29))
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别名
- VPS29
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背景
- FUNCTION: Essential component of the retromer complex a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). Has no activity towards p-nitrophenylphosphate p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). CATALYTIC ACTIVITY: O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate. COFACTOR: Binds 2 zinc ions per subunit. SUBCELLULAR LOCATION: Cytoplasm. Membrane, Peripheral membrane protein. Endosome membrane, Peripheral membrane protein.
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UniProt
- Q9QZ88
抗原
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