Dr TRPL (4th Cytoplasmic Loop) 抗体
This 兔 多克隆 antibody specifically detects Dr TRPL in IHC 和 WB. It exhibits reactivity toward Drosophila melanogaster.
产品编号 ABIN351175
发货至:
中国
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Quick Overview for Dr TRPL (4th Cytoplasmic Loop) 抗体 (ABIN351175)
抗原
Dr TRPL
适用
Drosophila melanogaster
宿主
兔
克隆类型
多克隆
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
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抗原表位
- 4th Cytoplasmic Loop
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原理
- Rabbit antibody to dr TRPL
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特异性
- Specific for TRPL.
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交叉反应
- Drosophila melanogaster
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from 4th cytoplasmic loop of drosophila TRPL (Transient receptor potential like protein) conjugated to blue carrier protein was used as the antigen.
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亚型
- IgG
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应用备注
- IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- Dr TRPL
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背景
- FUNCTION: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Required for vision in the dark and in dim light. Binds calmodulin. Trp and trpl act together in the light response although it is unclear whether as heteromultimers or distinct units. Also forms a functional cation channel with trp-gamma. Activated by fatty acids metabolic stress inositols and GTP-binding proteins. SUBUNIT: Forms heteromultimers with trp-gamma and to a lower extent with trp. Interacts with FKBP59 in vivo and is found in the inaD signaling complex. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Note: In the dark there is 20 fold more rhabdomeral trpl protein forming plasma membrane channels than in the light. In the light the protein translocates to an intracellular compartment. Protein levels remain unchanged in light and dark conditions.
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UniProt
- P48994
抗原
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