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SYT1 抗体 (AA 10-60)

SYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN350924
发货至: 中国
  • 抗原 See all SYT1 抗体
    SYT1 (Synaptotagmin I (SYT1))
    抗原表位
    • 15
    • 14
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-60
    适用
    • 80
    • 70
    • 47
    • 11
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 91
    • 12
    • 6
    • 2
    • 1
    • 1
    克隆类型
    • 101
    • 12
    多克隆
    标记
    • 68
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYT1 antibody is un-conjugated
    应用范围
    • 68
    • 42
    • 36
    • 16
    • 13
    • 13
    • 12
    • 11
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Rabbit antibody to Synaptotagmin 1 (10-60)
    特异性
    Specific for SYTI.
    交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from AA 10-60 of rat Synaptotagmin 1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in mouse.
    亚型
    IgG
    Top Product
    Discover our top product SYT1 Primary Antibody
  • 应用备注
    IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    SYT1 (Synaptotagmin I (SYT1))
    别名
    Synaptotagmin 1 (SYT1 产品)
    背景
    FUNCTION: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner, these are neurexins syntaxin and AP2. COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains. SUBCELLULAR LOCATION: Cytoplasmic vesicle secretory vesicle synaptic vesicle. Cytoplasmic vesicle secretory vesicle chromaffin granule. Note: Synaptic vesicles and chromaffin granules. TISSUE SPECIFICITY: Predominantly expressed in rostral phylogenetically younger brain regions and in some endocrine tissues.
    UniProt
    P21707
    途径
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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