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SYT1 抗体 (AA 10-60)

This 兔 多克隆 anti-SYT1 antibody specifically detects SYT1 in WB 和 IHC. The antibody is reactive with 大鼠 samples.
产品编号 ABIN7699022
发货至: 中国
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Quick Overview for SYT1 抗体 (AA 10-60) (ABIN7699022)

抗原

See all SYT1 抗体
SYT1 (Synaptotagmin I (SYT1))

适用

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大鼠

宿主

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克隆类型

  • 98
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多克隆

标记

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This SYT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 10-60

    原理

    Rabbit antibody to Synaptotagmin 1 (10-60)

    特异性

    Specific for SYTI.

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    A synthetic peptide from AA 10-60 of rat Synaptotagmin 1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in mouse.

    亚型

    IgG
  • 应用备注

    IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    SYT1 (Synaptotagmin I (SYT1))

    别名

    Synaptotagmin 1

    背景

    FUNCTION: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner, these are neurexins syntaxin and AP2. COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains. SUBCELLULAR LOCATION: Cytoplasmic vesicle secretory vesicle synaptic vesicle. Cytoplasmic vesicle secretory vesicle chromaffin granule. Note: Synaptic vesicles and chromaffin granules. TISSUE SPECIFICITY: Predominantly expressed in rostral phylogenetically younger brain regions and in some endocrine tissues.

    UniProt

    P21707

    途径

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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