SUMO2/3 抗体 (N-Term)
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北京 101111
Quick Overview for SUMO2/3 抗体 (N-Term) (ABIN350886)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Rabbit antibody to SUMO 2 3
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特异性
- Specific for SUMO2 and SUMO3
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from the n-terminal of rat SUMO2 (Small ubiquitin-related modifier 2) conjugated to blue carrier protein was used as the antigen. The antigen is homologous in many species including human mouse and chicken.
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亚型
- IgG
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应用备注
- IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))
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别名
- SUMO 2 3
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背景
- Function: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport DNA replication and repair mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I and can be promoted by an E3 ligase such as PIAS1-4 RANBP2 or CBX4 Subcellular location: Nucleus
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UniProt
- P61959
抗原
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