RHOU 抗体 (Internal Region)
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北京 101111
Quick Overview for RHOU 抗体 (Internal Region) (ABIN7698946)
抗原
See all RHOU 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Rabbit antibody to RhoU
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特异性
- Specific for RhoU.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from the internal region of human Rho related GTP binding protein RhoU (CDC42 like GTPase 1 CDC42L1 Ryu GTPase) conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 90% identity with rat and mouse sequence.
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亚型
- IgG
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- RHOU (Ras Homolog Gene Family, Member U (RHOU))
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别名
- RhoU
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背景
- Function: Acts upstream of PAK1 to regulate the actin cytoskeleton adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Golgi apparatus membrane, Lipid-anchor. Cell junction ‰ focal adhesion. Cell projection ‰ podosome. Note: Localizes to podosomes in SRC-transformed cells. Tissue specificity: Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach small intestine brain skeletal muscle and placenta.
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UniProt
- Q7L0Q8
抗原
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