RHOB 抗体
Quick Overview for RHOB 抗体 (ABIN350804)
抗原
See all RHOB 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Sheep antibody to RhoB
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特异性
- Specific for RhOB.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide as a part of human rat mouse Rho-related GTP-binding protein RhoB (ARH6 ARHB H6) conjugated to an immunogenic carrier protein was used as the immunogen.
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亚型
- IgG
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anti-Ras Homolog Gene Family, Member B (RHOB) (Internal Region) antibody
RHOB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member B (RHOB) (AA 1-196) antibodyRHOB 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member B (RHOB) antibodyRHOB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member B (RHOB) (AA 1-196) antibodyRHOB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member B (RHOB) (AA 107-156) antibodyRHOB 适用: 人, 小鼠, 大鼠, Cow, 山羊, 马, Pig, 绵羊, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member B (RHOB) antibodyRHOB 适用: 人 DB 宿主: 小鼠 Monoclonal 2916C2a unconjugated
anti-Ras Homolog Gene Family, Member B (RHOB) (AA 104-137) antibodyRHOB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14498 unconjugated
anti-Ras Homolog Gene Family, Member B (RHOB) (AA 103-137), (Middle Region) antibodyRHOB 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- RHOB (Ras Homolog Gene Family, Member B (RHOB))
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别名
- RhoB
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背景
- FUNCTION: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. SUBUNIT: Binds ROCK1 and ROCK2. Also binds PKN1/PRK1. Interacts with ARHGEF3 and AKAP13. Interacts with RTKN. SUBCELLULAR LOCATION: Late endosome membrane, Lipid-anchor. Cell membrane, Lipid-anchor. Nucleus. Note: Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. INDUCTION: By UV irradiation N-methyl-N-nitrosourea cisplatin cyclohexamide and serum stimulation.
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UniProt
- P62745
抗原
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