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Rho-related GTP-binding protein 抗体

RhO (pan) 适用: 人 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN350723
发货至: 中国
  • 抗原 See all Rho-related GTP-binding protein (RhO (pan)) 抗体
    Rho-related GTP-binding protein (RhO (pan))
    适用
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    • 1
    • 1
    • 1
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    宿主
    • 20
    • 9
    绵羊
    克隆类型
    • 18
    • 11
    多克隆
    标记
    • 24
    • 2
    • 2
    • 1
    This Rho-related GTP-binding protein antibody is un-conjugated
    应用范围
    • 21
    • 19
    • 15
    • 6
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    • 2
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Sheep antibody to pan RhO
    特异性
    Specific for RhO family.
    交叉反应
    人, 小鼠, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from AA of 50-100 of human RhOA conjugated to blue carrier protein was used as the antigen.
    亚型
    IgG
    Top Product
    Discover our top product RhO (pan) Primary Antibody
  • 应用备注
    IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    Rho-related GTP-binding protein (RhO (pan))
    别名
    pan RhO (RhO (pan) 产品)
    背景
    The protein encoded by this gene is a small GTPase of the Rho-subfamily which regulates signaling pathways that control diverse cellular functions including cell morphology migration endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42 and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP) which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
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