GPR143 抗体 (4th Cytoplasmic Domain)
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Quick Overview for GPR143 抗体 (4th Cytoplasmic Domain) (ABIN7698837)
抗原
See all GPR143 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 4th Cytoplasmic Domain
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原理
- Rabbit antibody to OA1
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特异性
- Specific for OA1.
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交叉反应
- 人
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from the 4th cytoplasmic domain of human OA1 conjugated to blue carrier protein was used as the antigen.
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亚型
- IgG
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anti-G Protein-Coupled Receptor 143 (GPR143) (AA 225-239), (Intracellular) antibody
GPR143 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 143 (GPR143) (AA 1-424) antibodyGPR143 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 143 (GPR143) (AA 314-404) antibodyGPR143 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- GPR143 (G Protein-Coupled Receptor 143 (GPR143))
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别名
- OA1
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背景
- Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. FUNCTION: Not known, binds heterotrimeric G proteins. SUBCELLULAR LOCATION: Melanosome membrane, Multi-pass membrane protein. Note: Targeted to intracellular organelles namely the melanosomes in pigment cells. TISSUE SPECIFICITY: Exclusively expressed in pigment cells. DISEASE: Defects in GPR143 are the cause of ocular albinism type 1 (OA1), also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity retinal hypopigmentation and the presence of macromelanosomes.
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UniProt
- P51810
抗原
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